Before 1937 little attention is paid in the literature to the etiology of endometritis in the bitch, bacteriological infection being considered as the principle cause. Of great importance in this condition is the endometritis, which occurs after oestrus.
For a long time the remarkably high percentage of cases of endometritis, which develop in older dogs has been observed; the graph shows a marked rise at the age of seven years. Moreover these bitches were either virgin or had had no litter for some years prior to the disorder. This causes a functional deterioration which predisposes to a lowered resistance to bacteria, and is responsible for the inadequate propulsion of the mucosal secretion through the long narrow cornus uteri.
Investigations were therefore made on the types of bacteria present and on the possibility of stimulating an endometritis with bacteria derived either from the purulent contents or from the pure culture bacteria