SERUM 5α-DIHYDROTESTOSTERONE AND TESTOSTERONE CHANGES WITH AGE IN MAN

in European Journal of Endocrinology
Restricted access

ABSTRACT

Serum 5α-dihydrotestosterone (DHT) and testosterone (T) were measured in 98 normal adult men aged between 20–80 years, separating T and DHT by thin layer chromatography and using a sensitive and reliable radioimmunoassay. In three age groups between 20–40, 40–60 and 60–80, the means ± sem for serum DHT were 84 ± 4, 79 ± 3 and 67 ± 3 (ng/100 ml) respectively. The corresponding values for testosterone were 559 ± 25, 491 ± 25 and 475 ± 28 (ng/100 ml). A significant decrease was observed in the DHT level of the 60–80 years age group compared to either the 20–40 (P < 0.01) or the 40–60 (P < 0.02) age groups. There was a moderate decline in the testosterone level of the 60–80 years age group compared to 20–40 years (P < 0.05) but there were no significant changes in the testosterone levels between other groups.

 

     European Society of Endocrinology

Related Articles

Article Information

Metrics

All Time Past Year Past 30 Days
Abstract Views 145 145 12
Full Text Views 101 101 0
PDF Downloads 67 67 0

Altmetrics

Cited By

PubMed

Google Scholar