Autoradiographic binding studies with [3H]oestradiol and [3H]dihydrotestosterone in the autonomic genital ganglion (plexus of Frankenhäuser) of the mouse

in European Journal of Endocrinology
View More View Less
Restricted access

Abstract. Male, female and Tfm mice (testicular feminization) were injected with [3H]oestradiol or [3H]dihydrotestosterone, and autoradiograms prepared of male accessory sex organs and of the cervico-vaginal portion of the female reproductive tract.

After injection of [3H]oestradiol in male, female and Tfm animals a nuclear concentration of radioactivity was found in a subpopulation – about 20–30% – of the neurons of the genital ganglion. No such concentration was seen after [3H]dihydrotestosterone. The results suggest a direct genomic effect of oestradiol on certain neurons of the autonomic genital ganglion in both sexes.

 

     European Society of Endocrinology

Sept 2018 onwards Past Year Past 30 Days
Abstract Views 167 41 2
Full Text Views 47 0 0
PDF Downloads 26 0 0