Prostaglandin D2 stimulates secretion of luteinizing hormone from pituitary gland in vitro

in European Journal of Endocrinology
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Abstract. The effect of prostaglandin D2 on the release of luteinizing hormone was studied in a superfusion system by superfusing human pituitary gland. Perfusion with 30 μg of prostaglandin D2 induced a significant increase of luteinizing hormone secretion. This is the first evidence of a direct effect of prostaglandin D2 on the secretion of luteinizing hormone from the human pituitary gland. This finding suggests the possible role of prostaglandin D2 in human reproductive function

 

     European Society of Endocrinology

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