Methodology articles


The Editorial Board of EJE understands the many challenges clinical and translational researchers face when trying to bring their research to publication. To address this, and to support our global endocrine community, the Editorial Board is continually commissioning a series of editorials aimed at improving key aspects of scientific methodology.

By learning from these editorials, implementing the recommendations and avoiding the common mistakes that many researchers make, you best place yourself to produce research of the highest quality and soundness of science.

This collection represents a valuable opportunity to further your research, increase its scientific quality and ultimately improve your chances of citation.


Multiple testing: when is many too much?
Rolf H H Groenwold, Jelle J Goeman, Saskia Le Cessie, and Olaf M Dekkers

Introduction to diagnostic test accuracy studies
Alice J Sitch, Olaf M Dekkers, Barnaby R Scholefield, and Yemisi Takwoingi

When observational studies can give wrong answers: the potential of immortal time bias
Olaf M Dekkers and Rolf H H Groenwold

Study design: what’s in a name?
Olaf M Dekkers and Rolf H H Groenwold

Missing data: the impact of what is not there
Rolf H H Groenwold and Olaf M Dekkers

Measurement error in clinical research, yes it matters
Rolf H H Groenwold and Olaf M Dekkers

METHODOLOGY FOR THE ENDOCRINOLOGIST: Basic aspects of confounding adjustment
Rolf H H Groenwold and Olaf M Dekkers

Who is afraid of non-normal data? Choosing between parametric and non-parametric tests
Saskia le Cessie, Jelle J Goeman and Olaf M Dekkers

Why not to (over)emphasize statistical significance
Olaf M Dekkers