Prostaglandin D2 stimulates secretion of luteinizing hormone from pituitary gland in vitro

in European Journal of Endocrinology
Authors:
Akira Miyake
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Keiichi Tasaka
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Shintaro Mori
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Youichi Saito
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Toshihiro Aono
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Abstract. The effect of prostaglandin D2 on the release of luteinizing hormone was studied in a superfusion system by superfusing human pituitary gland. Perfusion with 30 μg of prostaglandin D2 induced a significant increase of luteinizing hormone secretion. This is the first evidence of a direct effect of prostaglandin D2 on the secretion of luteinizing hormone from the human pituitary gland. This finding suggests the possible role of prostaglandin D2 in human reproductive function

 

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     European Society of Endocrinology

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