BIOLOGICAL METHODS FOR DETERMINATION OF POTENCY OF GROWTH HORMONE PREPARATIONS

in European Journal of Endocrinology
Author:
TAGE KEMP
Search for other papers by TAGE KEMP in
Current site
Google Scholar
PubMed
Close
Restricted access

USD  $0.01
USD  $0.01

USD  $0.01
USD  $0.01

USD  $0.01
USD  $0.01

Two papers published recently in this journal by Dingemanse, Freud & Uyldert (p. 71, 1948) and by Gjeddebæk (p. 258, 1948) discuss the various biological methods for determining the potency of growth hormone preparations.

Dingemanse et al. propose to designate the growth hormone as chondrotrophin and prefer to speak of chondrotrophin rather than somatotrophin (Selye). The reason for introducing the new expression chondrotrophin is, however, not quite obvious. No evidence at all proves the existence of an independent chondrotrophic hormone or preparation, such a substance has not been isolated yet.

The typical many-sided effect of growth hormone preparations has, as regards hereditary pituitary dwarfism in mice, been proved many years ago by Kemp in a paper, published 1934, also demonstrating for the first time the possibility of using dwarf mice for potency determinations of growth hormone preparations. In this publication Kemp (1. c. p. 1855) emphasises: »... dass bei Zwergmäusen

 

  • Collapse
  • Expand

     European Society of Endocrinology

Sept 2018 onwards Past Year Past 30 Days
Abstract Views 40 40 2
Full Text Views 0 0 0
PDF Downloads 0 0 0